Table 2. Properties of the growth-coupled overproducer designs under heterotrophic conditions.
| Heterotrophic conditions (0.0743) | |||||
|---|---|---|---|---|---|
| Metabolite |
Maximun production rate |
Number of knockouts |
Growth rate |
Production rate (mmol.gDW−1h−1) |
BPCY |
| (mmol.gDW−1h−1) |
(h−1) |
||||
| Fumarate (4C) |
1.462 |
4 |
0.045 |
0.719 |
0.0324 |
| Ethanol (2 C) |
1.901 |
2 |
0.035 |
1.218 |
0.0426 |
| 1-Butanol (4 C) |
0.951 |
4 |
0.036 |
0.559 |
0.0199 |
| Sucrose (12 C) |
0.443 |
5 |
0.062 |
0.053 |
0.0033 |
| Lactate (3 C) |
1.867 |
3 |
0.023 |
1.444 |
0.0366 |
| H2 | 10.926 | 7 | 0.019 | 3.195 | 0.062 |
LLS, Light limiting state; CLS, Carbon limiting state; BPCY, Biomass-product coupled yield. Numbers inside parenthesis represent the wild-type growth rate.