Table 3. Assessed fecal microbiota in subjects with IBS at baseline and after four and eight weeks of daily treatment with B. infantis 35624 or placebo and after 2 weeks of post-supplementation follow-up.
| Microbiota | Study Visit | Treatment groups | |||
|---|---|---|---|---|---|
| |
|
B. infantis 35624 (log 10 ng DNA g−1) |
Placebo (log 10 ng DNA g−1) |
|
|
| |
|
Mean (SE) |
Mean (SE) |
Difference (SE) |
p-value |
| Bifidobacterium catenlatum gp. |
Baseline |
1.96 (0.377) |
1.55 (0.409) |
|
|
| |
Week 4 |
1.44 (0.088) |
1.36 (0.095) |
0.07 (0.129) |
0.566 |
| |
Week 8 |
1.63 (0.132) |
1.62 (0.143) |
0.01 (0.195) |
0.945 |
| |
Follow-up |
1.53 (0.166) |
1.51 (0.178) |
0.02 (0.243) |
0.948 |
| Clostridium perfringens gp. |
Baseline |
1.38 (0.141) |
1.23 (0.153) |
|
|
| |
Week 4 |
1.01 (0.107) |
1.13 (0.116) |
-0.13 (0.158) |
0.428 |
| |
Week 8 |
1.06 (0.106) |
1.24 (0.115) |
-0.18 (0.157) |
0.265 |
| |
Follow-up |
1.15 (0.108) |
1.35 (0.117) |
-0.19 (0.159) |
0.227 |
| Enterococcus spp |
Baseline |
2.31 (0.115) |
2.34 (0.125) |
|
|
| |
Week 4 |
2.35 (0.082) |
2.38 (0.090) |
-0.03 (0.122) |
0.809 |
| |
Week 8 |
2.25 (0.097) |
2.21 (0.105) |
0.04 (0.143) |
0.770 |
| |
Follow-up |
1.99 (0.102) |
1.92 (0.111) |
0.07 (0.151) |
0.665 |
| Bacteroides-Prevotella- Porphymonas |
Baseline |
5.80 (0.040) |
5.86 (0.044) |
|
|
| |
Week 4 |
5.81 (0.031) |
5.78 (0.034) |
0.02 (0.045) |
0.639 |
| |
Week 8 |
5.78 (0.030) |
5.76 (0.033) |
0.03 (0.044) |
0.541 |
| Follow-up | 5.74 (0.034) | 5.70 (0.038) | 0.03 (0.051) | 0.494 | |
Post-baseline means are least squares means from the statistical mixed model.