. Author manuscript; available in PMC: 2013 Nov 30.

Published in final edited form as: Nature. 2013 May 12;497(7451):647–651. doi: 10.1038/nature12139

Table 1.

Mutagenesis and functional study of key residues important for nitrate/nitrite exchange.

NarK (E. coli)	NarU (E. coli)	NrtA (A. nidulans)	Colony growth on nitrate
R89	R87K^a R87P^a	R87K^b R87T^b	+ -
N175		N168A^c N168Q^b N168C^b	- - -
Y263	Y261Q^a Y261N^a		+ +
R305	R303Q^a R303C^a	R368K^b R368Q^b R368C^b	+ - -
A415		N459A^c N459Q^b N459K^b N459C^b	- + - -

Study published by reference ¹⁰

Study published by reference ²⁴

Study published by reference ²¹

See references above for a comprehensive list of all available mutagenesis data.