Table 2.

Overall and age-specific risk of suicide in offspring of schizophrenic parents combined and for mothers and fathers separately.

	Number of pairs		OR (95% CI)
	Cases	Controls	Crudea	Adjustedb	Adjustedc	Adjustedd
Parents
Total	39088	194074	2.27 (2.00–2.59)	2.08 (1.82–2.37)	2.05 (1.79–2.34)	1.73 (1.47–2.04)
Adolescents (12–18 y)	9171	44748	2.36 (1.80–3.10)	2.19 (1.66–2.88)	2.09 (1.58–2.75)	1.99 (1.49–2.65)
Young adults (19–25y)	18062	89388	2.10 (1.73–2.55)	1.77 (1.44–2.82)	1.75 (1.43–2.16)	1.58 (1.23–2.01)
Adults (26–30y)	11856	59859	2.20 (1.75–2.76)	1.99 (1.58–2.51)	1.98 (1.57–2.50)	1.52 (1.13–2.06)
Mothers
Total	20469	100888	2.28 (1.94–2.68)	2.08 (1.76–2.45)	2.03 (1.71–2.39)	2.00 (1.38–2.90)
Adolescents (12–18 y)	4698	22825	2.46 (1.74–3.47)	2.25 (1.59–3.18)	2.05 (1.35–3.24)	2.11 (1.60–2.79)
Young adults (19–25y)	9403	46192	1.88 (1.48–2.40)	1.60 (1.23–2.07)	1.57 (1.21–2.04)	1.45 (1.06–2.00)
Adults (26–30y)	6369	31899	2.37 (1.81–3.10)	2.11 (1.60–2.79)	2.10 (1.59–2.77)	1.63 (1.13–2.35)
Fathers
Total	19330	93683	2.26 (1.82–2.80)	2.07 (1.67–2.58)	2.08 (1.67–2.58)	1.78 (1.38–2.30)
Adolescents (12–18 y)	4473	21923	2.22 (1.44–3.44)	2.11 (1.36–3.25)	2.09 (1.35–3.24)	1.92 (1.22–3.03)
Young adults (19–25y)	8659	43196	2.58 (1.88–3.56)	2.13 (1.52–3.00)	2.15 (1.53–3.02)	1.84 (1.27–2.66)
Adults (26–30y)	5487	27960	1.86 (1.23–2.80)	1.75 (1.16–2.62)	1.75 (1.16–2.62)	1.29 (0.79–2.13)

^aCrude estimates were adjusted for sex, age and country of birth through matching

^bThe estimates were further adjusted for socioeconomic status (SES)

^cThe estimates were further adjusted for SES and parental suicide

^dThe estimates were further adjusted for SES, parental suicide, and offspring mental illness.