Table 1.
Characteristics of the control and MDD groups.
| Controls | n | MDD | n | t, F, Chi | p | |
|---|---|---|---|---|---|---|
| Age (yr) | 36.42 ± 12.13 | 19 | 37.00 ± 10.77 | 20 | −1.58 | 0.88 |
| Sex (% male) | 37.00% | 19 | 35.00% | 20 | 0.12 | 0.91 |
| BMI | 24.48 ± 3.73 | 19 | 24.78 ± 4.29 | 20 | −0.23 | 0.82 |
| Ethnicity | 19 | 20 | 0.84 | 0.84 | ||
| Caucasian | 73.68% | 70.00% | ||||
| African-American | 15.79% | 10.00% | ||||
| Asian | 5.26% | 10.00% | ||||
| Other or mixed | 5.26% | 10.00% | ||||
| Current tobacco use (%) | 19 | 20 | 2.30 | 0.32 | ||
| None | 89.47% | 75.00% | ||||
| Some days | 10.53% | 15.00% | ||||
| Daily | 0.00% | 10.00% | ||||
| Lifetime tobacco use (%) | 42.11% | 19 | 50.00% | 20 | 0.48 | 0.63 |
| IDS | 4.95 ± 4.89 | 19 | 37.21 ± 9.59 | 14 | −11.53 | 0.00 |
| F2-IsoP (ng/ml) | 0.044 ± 0.015 | 19 | 0.043 ± 0.016 | 19 | 0.11 | 0.75 |
| IL-6 (pg/ml) | 0.73 ± 0.37 | 18 | 0.84 ± 0.823 | 20 | 0.75 | 0.39 |
| IL-10 (pg/ml) | 0.55 ± 0.61 | 18 | 0.40 ± 0.66 | 19 | 0.03 | 0.87 |
| IL-6/IL-10 | 8.63 ± 12.21 | 18 | 11.68 ± 14.20 | 19 | 0.00 | 0.95 |
Data are means ± SD of raw data. p values for IL-6, IL-10, IL-6/IL-10, and F2-IsoP were derived from natural log-transformed data. Between-group means comparisons were assessed by univariate ANCOVA for F2-isoP’s and IL-6, adjusted for BMI, and IL-10 and IL-6/IL-10, adjusted for current tobacco use. The sample sizes above were not identical across all variables where data were missing.