Table 2.

Baseline measurements vs. Week 8 of sertraline treatment for MDD group.

	Baseline	Week 8	n	Paired-t	p
HDRS	18.71 ± 3.22	10.24 ± 6.32	17	5.23	<.001
F2-IsoP (ng/ml)	0.047 ± 0.016	0.048 ± 0.019	13	0.07	0.94
IL-6 (pg/ml)	0.96 ± 0.84	1.31 ± 0.98	17	−2.37	0.03
IL-10 (pg/ml)	0.27 ± 0.35	0.37 ± 0.62	17	−0.19	0.85
IL-6/IL-10	12.92 ± 14.52	16.06 ± 16.19	17	−1.62	0.13

Data are means ± SD of raw data. p values were calculated using paired-sample t-tests of log-transformed F2-IsoP and cytokine values. Certain sample sizes and baseline values for the MDD’s in this table differ from those in Table 1, because only MDD’s with both baseline and Week 8 data are included in Table 2.