Table 1. Characteristics of the mutations within the lacI gene in Msh2 WT and Msh2−/− macrophages that were SNAP-treated or untreated.
Msh2+/+ (%) | Msh2−/− (%) | Msh2 −/− SNAP (%) | |
Transitions | 3 (42.8) | 6 (42.9) | 15 (68.2) |
C:G→T:A all | 3 (42.8) | 5 (35.7) | 13 (59.1) |
CpG sites | 3 (42.8) | 3 (21.4) | 8 (36.4) |
Non CpG sites | 0 (0) | 2 (14.3) | 5 (22.7) |
TA→C:G | 0 (0) | 1 (7.1) | 2 (9.1) |
Transversions | 3 (42.8) | 4 (28.6) | 5 (22.7) |
C:G→T:A | 2 (28.6) | 1 (7.1) | 1 (4.5) |
C:G→G:C | 1 (14.3) | 0 (0) | 0 (0) |
T:A→G:C | 0 (0) | 1 (7.1) | 3 (13.6) |
T:A→A:T | 0 (0) | 2 (14.3) | 1 (4.5) |
Insertions/deletions | 1 (14.3) | 4 (28.6) | 2 (9.1) |
Insertions | 0 (0) | 2 (14.3) | 0 (0) |
Deletions | 1 (14.3) | 2 (14.3) | 2 (9.1) |
Total mutations | 7 (100) | 14 (100) | 22 (100) |