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. Author manuscript; available in PMC: 2014 Jun 1.
Published in final edited form as: Clin Chem. 2013 Feb 20;59(6):949–958. doi: 10.1373/clinchem.2012.196949

Fig. 2.

Fig. 2

Superposition of the theoretical relationship (solid and dashed curves) between HDL diameter and HDL-C/ApoA-I ratio derived from the updated Shen model on the scatter plot/heat plot of the WHS data (Fig. 1). The theoretical curves also depend on the molar ratio of triglyceride-to-cholesterol ester in the hydrophobic core of the particles (TG/CEcore) and the fraction of ApoA-I in the HDL proteome (FApoA-I). See Supplemental Data for a derivation of the theoretical relationship based on the updated Shen model.