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. 2013 May 31;8(5):e65561. doi: 10.1371/journal.pone.0065561

Figure 7. Inhibition of IL-6, IL-8, PGE2 and VEGF by A2A or A3AR agonists and PEMFs in T/C-28a2 chondrocytes.

Figure 7

Effect of A2AAR agonist and antagonist (CGS 21680, 100 nM; SCH 442416, 1 µM) or A3AR agonist and antagonist (Cl-IB-MECA, 100 nM; MRS 1334, 1 µM) on IL-6 (A), IL-8 (B), PGE2 (C) or VEGF (D) production in the absence or in the presence of PEMF exposure for 24 hours in T/C-28a2 chondrocytes stimulated with IL-1β (1 ng/ml). Results are reported as the mean ± SEM of four independent experiments. *, p<0.05; **, p<0.01.