Table 3. Comparison of HIV-1 genotype distributions among IDUs in Dehong and Myanmar.
Year of sampling | Region of sampling | Number of samples | Genome regions analyzed | Genotype | P-value† | ||||
B′/C | B′ | C | Other* | ||||||
Present Study | 2005–2009 | Dehong | 91 | pol | 75 (82.4) | 5 (5.5) | 5(5.5) | 6 (6.6) | - |
Pang etal. [20] | 2009 | Northern Myanmar | 79 | gag p17, pol, vif-env C2V3 | 37(46.8) | 3(3.8) | 6(7.6) | 33(41.8) | <0.001 |
Takebe.etal. [27] | 1999–2000 | Central Myanmar | 21 | gag p17,envC2/V3 | 2(9.5) | 7(33.3) | 4(19.0) | 8(38.1) | <0.001 |
Qiu. etal. [15] | 1996–1998 | Dehong | 54 | env C2V3,near-full-length sequences | 4(7.4) | 49 (90.7) | 1(1.9) | 0 | <0.001 |
Yang. etal. [11] | 2000–2001 | Dehong | 14 | gag-RTenv C2V3 | 9(64.3) | 4 (28.6) | 0 | 1 (7.1) | 0.032 |
Zhang. et al. [16] | 2003 | Dehong | 13 | gag p17 and RT | 8(61.5) | 2 (15.4) | 0 | 3 (23.1) | 0.087 |
The “other” category is used to group subjects with more rare genotypes including B′/C/CRF01_AE and C/CRF01_AE recombinants and pure CRF01_AE.
Statistical significance of the distribution of genotypes between previous study and present study was determined by Fisher's exact test.