Table 1. Characteristics of studies about ABT and hepatocellular carcinoma included in the meta-analysis.
Author | PublicationYear | Study type | Number of patients | ABTRate (%) | Age(mean,Y) | Sex(male%) | LiverCirrhosis(%) | Child A(%) | TNM stage | TransfusedUnits | Study quality | |||
ABT+ | ABT− | Total | I+II | III+IV | ||||||||||
Matsumata et al16 | 1993 | RCS | 54 | 72 | 126 | 42.86 | 57.6 | 83.3 | 56.5 | 9 | ||||
Itasaka et al17 | 1995 | PCS | 38 | 33 | 71 | 53.52 | 58.1 | 85.9 | 90.1 | 94.4 | 9.9 | 9 | ||
Yamamoto et al18 | 1996 | RCS | 85 | 301 | 386 | 22.02 | 59.7 | 80.6 | 59.3 | 68.7 | 6 | |||
Asahara et al19 | 1999 | RCS | 23 | 152 | 175 | 13.14 | 60.1 | 76.0 | 70.3 | 75 | 56 | 8 | ||
Makino et al20 | 2000 | RCS | 117 | 78 | 195 | 60.00 | 60.8 | 80.0 | 71.3 | 67.7 | 9 | |||
Kitagawa et al21 | 2001 | PCS | 26 | 52 | 78 | 33.33 | 60.0 | 55.5 | 7 | |||||
Kwon et al9 | 2001 | PCS | 53 | 55 | 108 | 49.07 | 62.0 | 76.9 | 48.2 | 80.0 | 108 | 0 | 5.3 | 9 |
Ercolani et al22 | 2002 | RCS | 71 | 153 | 224 | 31.07 | 62.5 | 81.3 | 78.6 | 82.6 | 6 | |||
Sasaki et al23 | 2002 | PCS | 23 | 52 | 75 | 30.67 | 61.7 | 78.7 | 61,3 | 55 | 20 | 5 | ||
Wei et al24 | 2003 | RCS | 45 | 110 | 155 | 29.03 | 52.0 | 78.7 | 34.9 | 3.5 | 6 | |||
Hanazaki et al8 | 2005 | RCS | 210 | 158 | 368 | 57.07 | 62.4 | 75.6 | 52.2 | 78.3 | 300 | 68 | 9 | |
Laurent et al25 | 2005 | RCS | 36 | 72 | 108 | 33.33 | 64.0 | 82.4 | 63.0 | 68 | 40 | 6 | ||
Sasaki et al26 | 2006 | RCS | 184 | 233 | 417 | 44.12 | 74.2 | 67.9 | 74.2 | 339 | 78 | 8 | ||
Sugita et al27 * | 2008 | RCS | 101 | 120 | 221 | 45.70 | 63.2 | 77.0 | 54.5 | 7.9 | 9 | |||
Kaibori et al28 | 2008 | RCS | 269 | 141 | 410 | 65.61 | 64.2 | 79.8 | 39.5 | 264 | 136 | 5.0 | 9 | |
Wang et al29 | 2009 | RCS | 62 | 411 | 473 | 13.11 | 53.1 | 80.1 | 44.4 | 83.3 | 400 | 73 | 8 | |
Choi et al30 | 2009 | RCS | 91 | 96 | 187 | 48.66 | 51.0 | 75.4 | 56.7 | 99 | 88 | 6 | ||
Abdel-Wahab et al31 | 2010 | RCS | 87 | 72 | 159 | 54.72 | 54.8 | 75.0 | 87.0 | 138 | 37 | 3.0 | 7 | |
Nanashima et al32 | 2011 | RCS | 100 | 83 | 183 | 54.64 | 65.0 | 80.9 | 7 | |||||
Okamura et al33 | 2011 | RCS | 87 | 289 | 376 | 23.14 | 61.4 | 80.6 | 94.2 | 213 | 163 | 7 | ||
Yang et al34 | 2011 | RCS | 164 | 141 | 305 | 53.77 | 49.2 | 91.5 | 76.7 | 88.5 | 117 | 188 | 5.8 | 7 |
Kuroda et al35 | 2012 | RCS | 76 | 759 | 835 | 9.10 | 63.5 | 76.9 | 51.6 | 85.4 | 4.2 | 9 |
ABT+, allogenenic blood transfused; ABT−, non-allogenenic blood transfused; RCS, retrospective cohort study; PCS, prospective cohort study.
Study provided cancer-related death data and could not be included.