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. 2013 May 31;8(5):e64261. doi: 10.1371/journal.pone.0064261

Table 1. Characteristics of studies about ABT and hepatocellular carcinoma included in the meta-analysis.

Author PublicationYear Study type Number of patients ABTRate (%) Age(mean,Y) Sex(male%) LiverCirrhosis(%) Child A(%) TNM stage TransfusedUnits Study quality
ABT+ ABT− Total I+II III+IV
Matsumata et al16 1993 RCS 54 72 126 42.86 57.6 83.3 56.5 9
Itasaka et al17 1995 PCS 38 33 71 53.52 58.1 85.9 90.1 94.4 9.9 9
Yamamoto et al18 1996 RCS 85 301 386 22.02 59.7 80.6 59.3 68.7 6
Asahara et al19 1999 RCS 23 152 175 13.14 60.1 76.0 70.3 75 56 8
Makino et al20 2000 RCS 117 78 195 60.00 60.8 80.0 71.3 67.7 9
Kitagawa et al21 2001 PCS 26 52 78 33.33 60.0 55.5 7
Kwon et al9 2001 PCS 53 55 108 49.07 62.0 76.9 48.2 80.0 108 0 5.3 9
Ercolani et al22 2002 RCS 71 153 224 31.07 62.5 81.3 78.6 82.6 6
Sasaki et al23 2002 PCS 23 52 75 30.67 61.7 78.7 61,3 55 20 5
Wei et al24 2003 RCS 45 110 155 29.03 52.0 78.7 34.9 3.5 6
Hanazaki et al8 2005 RCS 210 158 368 57.07 62.4 75.6 52.2 78.3 300 68 9
Laurent et al25 2005 RCS 36 72 108 33.33 64.0 82.4 63.0 68 40 6
Sasaki et al26 2006 RCS 184 233 417 44.12 74.2 67.9 74.2 339 78 8
Sugita et al27 * 2008 RCS 101 120 221 45.70 63.2 77.0 54.5 7.9 9
Kaibori et al28 2008 RCS 269 141 410 65.61 64.2 79.8 39.5 264 136 5.0 9
Wang et al29 2009 RCS 62 411 473 13.11 53.1 80.1 44.4 83.3 400 73 8
Choi et al30 2009 RCS 91 96 187 48.66 51.0 75.4 56.7 99 88 6
Abdel-Wahab et al31 2010 RCS 87 72 159 54.72 54.8 75.0 87.0 138 37 3.0 7
Nanashima et al32 2011 RCS 100 83 183 54.64 65.0 80.9 7
Okamura et al33 2011 RCS 87 289 376 23.14 61.4 80.6 94.2 213 163 7
Yang et al34 2011 RCS 164 141 305 53.77 49.2 91.5 76.7 88.5 117 188 5.8 7
Kuroda et al35 2012 RCS 76 759 835 9.10 63.5 76.9 51.6 85.4 4.2 9

ABT+, allogenenic blood transfused; ABT−, non-allogenenic blood transfused; RCS, retrospective cohort study; PCS, prospective cohort study.

*

Study provided cancer-related death data and could not be included.