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. 2013 May 31;8(5):e64301. doi: 10.1371/journal.pone.0064301

Figure 4. HSA-IL28B acts through IL28R1 and IL10R2.

Figure 4

Huh7.5.1 cells were infected with Jc1-Luc HCVcc (multiplicity of infection  = 0.1) 1 day before antibody neutralization and N-HSA-IL28B treatment. Anti-IL28R1 blocking antibody (A) or anti-IL10R2 blocking antibody (B) was added to infected cells and incubated for 2 h before washing. After receptor blocking, cells were further treated with 12 ng/mL N-HSA-IL28B for another 2 days. IgG isotype (20 µg/mL) was used as the negative control. Luciferase assays were performed to measure the propagation of HCVcc.