Table 1. Baseline characteristics of 279 fatal coronary heart disease cases and 279 matched controls. *,† .
MP-1 | MP-2 | |||||
Cases (n = 222) | Controls (n = 222) | P-value‡ | Cases (n = 57) | Controls (n = 57) | P-value‡ | |
Male gender, % | 70 | 70 | – | 79 | 79 | – |
Age, y | 50.5±7.4 | 50.5±7.5 | – | 51.7±7.1 | 51.8±7.2 | – |
Body mass index, kg/m2 | 26.9±4.7 | 26.0±3.9 | 0.02 | 27.7±4.8 | 26.2±3.8 | 0.07 |
Smoking, % | ||||||
Never | 18 | 32 | – | 18 | 35 | – |
Former | 21 | 30 | – | 26 | 39 | – |
Current | 61 | 38 | <0.0001 | 56 | 26 | 0.002 |
Alcohol consumption, % | ||||||
No intake | 38 | 34 | – | 23 | 12 | – |
Low to moderate | 34 | 36 | – | 44 | 67 | – |
High | 27 | 30 | 0.29 | 33 | 21 | 0.90 |
High educational level, % § | 7 | 14 | 0.008 | 21 | 18 | 0.82 |
Parental history of myocardial infarction, % | 9.5 | 8.7 | 0.87 | 5.3 | 5.3 | 1.00 |
Diabetes mellitus, % | 5.0 | 2.7 | 0.33 | 5.3 | 0 | 0.25 |
Systolic blood pressure, mm Hg | 134.5±21.0 | 125.5±15.6 | <0.0001 | 138.8±20.3 | 126.8±17.1 | 0.001 |
Diastolic blood pressure, mm Hg | 83.4±12.4 | 78.6±9.7 | <0.0001 | 85.6±12.1 | 79.7±9.9 | 0.002 |
Blood pressure lowering medication, % | 14.9 | 9.0 | 0.06 | 19.3 | 10.5 | 0.23 |
Hypertension, % | 46 | 28 | <0.0001 | 56 | 33 | 0.002 |
Plasma total cholesterol, mmol/l || | 6.5±1.3 | 5.9±1.1 | <0.0001 | 5.8±1.0 | 5.7±1.0 | 0.83 |
Plasma HDL-cholesterol, mmol/l || | 1.1±0.3 | 1.2±0.3 | 0.002 | 1.2 ±0.4 | 1.3±0.3 | 0.15 |
Cholesterol lowering medication, % | 1.8 | 0.5 | 0.25 | 1.8 | 0 | 1.00 |
Hypercholesterolemia, % | 42 | 27 | 0.001 | 26 | 19 | 0.42 |
Footnotes to Table 1.
Values are means ± SD, unless indicated otherwise.
Controls were matched on age, gender, cohort, and enrollment date.
Paired t-test for linear values and Wilcoxon signed-rank test for proportions.
Completed higher vocational training or university.
|| Non-fasting.