Table 3. Associations between plasma cholesteryl ester fatty acids and fatal CHD, matched by age, gender, cohort, and enrollment date.* .
Model 1 † | Model 2 ‡ | Model 3 § | |
OR (95% CI) | OR (95% CI) | OR (95% CI) | |
Combined cohorts | N = 558 | ||
Linoleic acid | 0.86 (0.74–1.00) | 0.89 (0.74–1.06) | 0.95 (0.78–1.15) |
Arachidonic acid | 1.00 (0.85–1.18) | 1.06 (0.88–1.27) | 1.11 (0.92–1.35) |
Alpha-linolenic acid | 1.05 (0.87–1.25) | 0.97 (0.79–1.19) | 0.92 (0.74–1.15) |
EPA | 1.02 (0.88–1.20) | 1.07 (0.90–1.26) | 1.04 (0.86–1.24) |
DHA | 1.02 (0.87–1.20) | 1.09 (0.91–1.31) | 1.12 (0.92–1.36) |
EPA+DHA | 1.03 (0.88–1.20) | 1.08 (0.91–1.27) | 1.06 (0.88–1.27) |
EPA: eicosapentaenoic acid, DHA: docosahexaenoic acid.
Values are odds ratios (95% CI) per standard deviation increase, based on conditional logistic models.
Crude model, matched for age, gender, cohort, and enrollment date.
Additional adjustment for smoking, BMI, education level, alcohol intake.
Additional adjustment for systolic blood pressure, total cholesterol.