Table 1. Effect of daidzein on plasma metabolistes and hormones of STD and HFD-fed rats¹.

	STD-vehicle	STD-daidzein	HFD-vehicle	HFD-daidzein
Glucose (md/dL)	154.13±11.6	148.6±10.6	184.5±17.5	148.6±5.8
Triglycerides (mg/dL)	109±12.4	105.1±11.02	174.5±16.8**	139.7±19.2
Total cholesterol (mg/dL)	67.4±6.2	59.6±2.6	86.2±3.4 *	83±3.7
HDL-cholesterol (mg/dL)	27.1±1.1	24.2±0.8 *	31.1±1.5 *	29.2±0.8
Insulin (ng/mL)	2.96±0.4	1.55±0.2*	5.02±0.5*	2.64±0.6#
Leptin (pg/mL)	1636±546	9217±1650**	1690±230	8329±2229#
Adiponectin (ng/mL)	4187±536	2602±217*	5603±308*	3457±289###
Testosterone (ng/mL)	1.93±0.2	1.49±0.1	2.41±0.2	1.78±0.1
17β-estradiol (pg/mL)	202.1±7.7	227.8±12.1	199.2±10.4	241.8±4.5##

¹Levels of plasma metabolites and hormones in rats fed STD or HFD and treated with vehicle or daidzein (50 mg/kg). Values represent the mean ± s.e.m. (n = 8). Two-way ANOVA and Bonferroni post test for multiple comparisons: *P<0.05, **P<0.01 vs. STD rats treated with vehicle; ^# P<0.05, ^## P<0.01, ^### P<0.001 vs. HFD rats treated with vehicle. Diet, treatment and interaction effects are described in the text.