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. 2013 May 31;8(5):e65034. doi: 10.1371/journal.pone.0065034

Table 1. Selected calcitriol-regulated genes involved in axogenesis and myelination.

DRG/SC Fold Change Gene Symbol Gene Name SC Fold Change
1.6 Acsl4 Acyl-CoA synthetase 4 1.7
Adm Adrenomedullin 2.3
1.55 Agtr1a Angiotensin II receptor 1a 1.6
Aqp1 Aquaporin 1 1.75
-2.6 Cdh2 Cadherin 2
1.5 Cdw92 Solute carrier family 44, member 1
-3.6 Chl1 Cell adhesion molecule with homology to L1CAM
Cacna1b Calcium channel, voltage-dependent, Nalpha1B -2.5
Clcf1 Cardiotrophin-like cytokine factor 1 3.1
Crlf1 Cytokine receptor-like factor 1 1.8
Cxcl12 Chemokine 12 1.9
Clu Clusterin 2.3
Got1 Glutamic-oxaloacetic transaminase 1 2
Igf1 Insulin-like growth factor 1 2.4
Klhl24 Kainate receptor-interacting protein for GluR6 1.7
1.8 Kras Kirsten rat sarcoma viral oncogene homolog
1.9 Limk1 LIM domain kinase 1
-2.9 Map1b Microtubule-associated protein 1B
Mapk8ip1 Mitogen-activated protein kinase 8 interact prot 1 1.8
Metrn Meteorin 1.8
1.7 Myc V-myc myelocytomatosis viral oncogene
-5.7 Mycbp2 MYC binding protein 2
1.6 Ncam1 Neural cell adhesion molecule 1
Ndrg2 NDRG family member 2 1.9
Nefm Neurofilament, medium polypeptide -3.9
1.9 Ppp3cb Protein phosphatase 3, catalytic subunit, beta
3.5 Ppp3r1 Protein phosphatase 3, regulatory subunit B alpha
2 Prx Periaxin
-2.1 Rbpj Rec signal binding prot for IgK J region
1.6 Rcan1 Regulator of calcineurin 1
1.7 Rhoa Ras homolog gene family, member A
Rtn4rl2 Nogo receptor-like 3 -2.1
1.6 Ryk Receptor-like tyrosine kinase
2.2 Spp1 Osteopontin 4
1.6 Strn3 Striatin, calmodulin binding protein 3
Thbs4 Thrombospondin 4 2.5
1.5 Trim2 Tripartite motif-containing 2
Tspan2 Tetraspanin 2 1.8
1.5 Ulk2 Unc-51 like kinase 2
Vegfa Vascular endothelial growth factor A 1.9

Selected list of transcripts, involved in axogenesis and myelination, whose expression is modified after the addition of calcitriol (100 nM), during 24 hours, to cultures of Schwann cells (SC) or co-cultures of DRG and SC. The symbol, the full name and the fold change of each gene are indicated. Under-expressed genes are in italic. Calcitriol-regulated genes in both Schwann cell and DRG/Schwann cell cultures are in bold.