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. 2013 May 31;8(5):e64263. doi: 10.1371/journal.pone.0064263

Figure 2. The influence of dietary restriction during gestation on sleep/wake architecture, body temperature, and spontaneous activity in adult offspring mice.

Figure 2

Diurnal changes of wakefulness (A), NREM sleep (B), and REM sleep (C). Mean bin size (D), number of episodes (E), and mean interval (F) in each sleep/wake state for all 24-hour recordings. Hourly time course of body temperature (G) and spontaneous activity (H). Spontaneous activity was averaged for each 6-hour period (I) across ZT0-6 (L1), ZT6-12 (L2), ZT12-18 (D1), and ZT18-24 (D2). Open bars and circles indicate AD mice. Closed bars and circles indicate DR mice. Data represent means ± SEM (A–F; n = 6, G–I; n = 5). *p<0.05 indicates a significant difference.