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. 2013 May 31;8(5):e64263. doi: 10.1371/journal.pone.0064263

Figure 7. Adenosinergic system responsiveness in adult offspring mice.

Figure 7

The influence of caffeine on immobility time (A) in the forced swim test. The effect of caffeine on latency to the onset of sleep (B) and EEG delta/theta ratios in NREM sleep (C). Gene expression related to the regulation of adenosine signaling in the hypothalamus (D) and cortex (E). Open bars and circles indicate AD mice. Closed bars and circles indicate DR mice. Arrows indicate the injection time (ZT0). Data represent means ± SEM (A; n = 9, B, C; n = 3, D, E; n = 6–7). **p<0.01 and *p<0.05 indicate a significant difference.