Figure 2. Urinary ATP and NGF levels determined before (A: ATP, nM and B: NGF, pg/ml) and after normalization to urine creatinine content (C: ATP/Cr, pmol/mg and D: NGF, pg/mg) in women with OAB (n = 34) and age-matched controls (n = 36).

Columns are mean values ± standard deviation (SD). *P<0.05 (unpaired Student’s t-test with Welch’s correction) represent significant differences from controls. In E and F, represented are the receiver-operator characteristics (ROC) curves of urinary ATP/Cr and urinary NGF/Cr in OAB patients, respectively. Please note that, for this cohort, ATP/Cr has a better area under de curve (AUC = 0.7407; 95% confidence interval (CI) = 0.62–0.86; P<0.001) than NGF/Cr (AUC = 0.5391; 95% CI = 0.39–0.69; P<0.001).