Skip to main content
. 2013 May 30;139(2):441–451. doi: 10.1007/s10549-013-2573-3

Table 2.

Efficacy endpoint analyses

Efficacy assessment Treatment group Hazard ratio (95 % CI)
n Exemestane n Anastrozole
ERIRC-assessed TTP (FAS), monthsa (95 % CI) 147 13.8 (10.8, 16.5) 145 11.1 (10.8, 16.6) 1.007 (0.771, 1.317)
Investigator-assessed TTP (FAS), monthsa (95 % CI) 147 13.8 (10.0, 16.6) 145 13.7 (10.9, 16.6) 1.059 (0.816, 1.374)
ERIRC-assessed TTP (PPS), monthsa (95 % CI) 142 13.8 (10.8, 16.5) 138 11.1 (9.2, 16.4) 0.977 (0.746, 1.280)
OS (FAS), monthsa (95 % CI) 147 NR (49.1, NR) 145 60.1 (4.2, NR) 1.062 (0.733, 1.539)
TTF (FAS), monthsa (95 % CI) 147 13.6 (9.2, 16.6) 145 11.1 (9.4, 14.1) 1.078 (0.854, 1.362)

Adapted with permission from Masuda et al. [24]

CI confidence interval, ERIRC expert radiologic images review committee, FAS full analysis set, NR not reached, OS overall survival, PPS per protocol set, TTF time to treatment failure, TTP time to progression

aMedian