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. 2013 May 30;139(2):441–451. doi: 10.1007/s10549-013-2573-3

Table 5.

Most common treatment-related adverse events occurring in ≥5 % of patients

Treatment-related adverse events Patients, n (%)
Exemestane (n = 149) Anastrozole (n = 149)
Grade Grade
Any 1–2 3–5 Any 1–2 3–5
Hot flush 33 (22) 33 (22) 0 22 (15) 22 (15) 0
Arthralgia 25 (17) 24 (16) 1 (1) 25 (17) 25 (17) 0
Musculoskeletal stiffness 17 (11) 17 (11) 0 11 (7) 11 (7) 0
GGT increased 15 (10) 11 (7) 4 (3) 5 (3) 4 (3) 1 (1)
Hypoesthesia 12 (8) 12 (8) 0 9 (6) 9 (6) 0
Body weight increased 11 (7) 11 (7) 0 5 (3) 5 (3) 0
ALP increased 9 (6) 9 (6) 0 5 (3) 5 (3) 0
Decreased appetite 9 (6) 8 (5) 1 (1) 6 (4) 6 (4) 0
Fatigue 8 (5) 8 (5) 0 2 (1) 2 (1) 0
Hypertension 8 (5) 7 (5) 1 (1) 10 (7) 8 (5) 2 (1)

Reproduced with permission from Masuda et al. [24]

ALP alkaline phosphatase, GGT gamma-glutamyl transferase

Based on Common Terminology Criteria for Adverse Events version 3.0 [44]