Table 1. Comparison of regional distribution of FITC-dextran in sclera, choroid-RPE, retina, and vitreous of ex-vivo albino rabbit eyes after suprachoroidal injection. Data are expressed as mean ± SD (n=4).
Tissue | Time (h) |
FITC-Dextran 4 kDa (µg/g of tissue) |
FITC-Dextran 40 kDa (µg/g of tissue) |
||||
---|---|---|---|---|---|---|---|
Injected side | Opposite side | Injected side: Opposite side Ratio | Injected side | Opposite side | Injected side: Opposite side Ratio | ||
Sclera |
1 h |
847.36±181.72 |
17.74±3.14 |
49.73±17.48 |
1111.34±593.69 |
23.60±4.32 |
44.94±19.12 |
3 h |
903.80±277.97 |
127.04±25.65 |
7.45±3.02 |
1558.15±656.68 |
216.03±81.61 |
8.01±3.84 |
|
Choroid-RPE |
1 h |
1329.31±369.76 |
20.39±14.86 |
187.74±256.07 |
2869.71±495.43 |
74.77±84.96 |
85.32±62.03 |
3 h |
796.84±368.76 |
137.08±49.71 |
5.77±1.05 |
1293.17±742.66 |
250.83±175.55 |
5.95±2.84 |
|
Retina |
1 h |
687.40±137.67 |
37.14±22.74 |
28.71±25.90 |
494.71±76.21 |
63.48±66.10 |
15.85±6.28 |
3 h |
344.51±275.03 |
56.06±15.50 |
7.39±7.72 |
57.77±24.11 |
30.22±10.26 |
2.18±1.30 |
|
Vitreous | 1 h |
6.10±2.31 |
2.22±3.46 |
17.09±14.03 |
4.30±3.56 |
0.92±0.46 |
4.02±2.55 |
3 h | 49.17±18.49 | 20.63±4.52 | 2.50±1.17 | 26.93±17.85 | 10.24±1.62 | 2.80±2.13 |