Table 3.
Mortality and Morbidity Following Subcutaneous Infection with Oshima 08-As and Oshima 5–10 in B6 Mice
| |
Oshima 08-AS |
Oshima 5–10 |
||||||
|---|---|---|---|---|---|---|---|---|
| Dose (pfu) | Morbiditya(%) | Mortality (%) | Day of onset (days) | Survival time (days) | Morbidity (%) | Mortality (%) | Day of onset (days) | Survival time (days) |
| 102 | 100 (5/5)b | 100 (5/5)c | 10.0±1.2 | 13.2±3.4 | 0 (0/5) | 0 (0/5) | — | — |
| 103 | 100 (5/5) | 60 (3/5) | 10.2±1.6 | 12.3±1.2 | 40 (2/5) | 0 (0/5) | 14.5±0.7 | — |
| 104 | 100 (5/5) | 60 (3/5) | 9.0±0.7 | 12.0±3.0 | 100 (5/5) | 60 (3/5) | 11.8±1.3 | 16.0±1.0 |
| 105 | 100 (5/5) | 60 (3/5) | 8.8±0.8 | 16.0±5.3 | 60 (3/5) | 40 (2/5) | 10.8±2.9 | 12.0±1.4 |
| 106 | 100 (5/5) | 100 (5/5) | 7.6±0.6 | 10.4±2.3 | 80 (4/5) | 20 (1/5) | 11.5±1.7 | 15 |
a
Morbidity of mice was estimated by >10% of weight loss.
b
Number of sick mice/number of infected mice.
c
Number of dead mice/number of infected mice.