Table 4.
Multivariate analysis for overall survival using variables including hENT1 and dCK
| Variable | Comparison | HR | 95% CI | P value |
|---|---|---|---|---|
| Primary tumor site |
Gallbladder vs. extrahepatic bile duct |
1.617 |
0.596 to 4.389 |
0.345 |
| Recurrence or unresectable |
Unresectable vs. recurrence |
1.707 |
0.511 to 5.700 |
0.384 |
| Histological type |
Poor vs. well/moderately |
1.117 |
0.354 to 3.519 |
0.851 |
| hENT1 expression |
High vs. low |
0.270 |
0.097 to 0.748 |
0.012 |
| dCK expression | High vs. low | 0.778 | 0.284 to 2.132 | 0.625 |
CI, confidence interval; dCK, deoxycytidine kinase; hENT1, human equilibrative nucleoside transporter; HR, hazard ratio.