Fig. 9.

Back-scattered SEM images of rat calvarial defects implanted with bioactive glass scaffolds at 6 weeks postimplantation: (a), (b) as-fabricated scaffolds; (c), (d) scaffolds pretreated for 3 days in aqueous phosphate solution; (e), (f) scaffolds pretreated for 3 days in aqueous phosphate solution and loaded with BMP-2. (NB = new bone; G = bioactive glass). The approximate thickness of the HA surface layer on the pretreated scaffolds prior to implantation is shown in (d) and (f).