Table IV.
Comparison of new bone formed in scaffolds composed of silicate 13-93 glass with different microstructures after implantation in rat calvarial defects (4.0–4.6 mm in diameter × 1.5 mm). The amount of new bone is shown as a percent of the available pore space (area) in the scaffolds and the total defect area.
| Microstructure of scaffolds | Porosity (%) | Pore size (μm) | New bone (%)
|
Implantation time (weeks) | Reference | |
|---|---|---|---|---|---|---|
| Available pore area | Total area | |||||
| Grid-like | 47 | 300 × 300 × 150 | 32 ± 13 | 18 ± 8 | 6 | This study |
| Trabecular | 80 | 100–500 | 25 ± 12 | 19 ± 9 | 12 | [12] |
| Oriented | 50 | 100–150 | 37 ± 8 | 18 ± 3 | 12 | [12] |
| Fibrous | 50 | 50–500 | 17* | 8.5 ± 2 | 12 | [32] |
*
Estimated from the total defect area