Table 3.
Multivariable associations of neuropathy and demographic and cancer-related factors with any functional impairment in cancer survivors with CIPN
| Predictor | Adjusted odds ratio estimate | |||
|---|---|---|---|---|
| Odds ratio | 95 % confidence interval | p | ||
| Age | 1.005 | 0.978 | 1.034 | 0.71 |
| Gender (female vs. male) | 1.552 | 0.800 | 3.064 | 0.19 |
| Race (white vs. non-white) | 0.335 | 0.143 | 0.781 | 0.01 |
| Marital status | ||||
| Married vs. widowed | 1.266 | 0.467 | 3.762 | 0.652 |
| Married vs. other | 1.061 | 0.541 | 2.135 | 0.866 |
| Education (≥partial college vs. HS or less) | 0.898 | 0.513 | 1.593 | 0.71 |
| Previous surgery (yes vs. no) | 0.684 | 0.301 | 1.574 | 0.37 |
| Previous RT (yes vs. no) | 0.809 | 0.445 | 1.463 | 0.48 |
| Cancer type | ||||
| Breast vs. other | 0.375 | 0.172 | 0.806 | 0.01 |
| Alimentary vs. other | 0.731 | 0.417 | 1.558 | 0.42 |
| Sensory neuropathy | 1.064 | 0.987 | 1.148 | 0.11 |
| Motor neuropathy | 1.262 | 1.166 | 1.375 | <0.0001 |
AUC for the ROC curve=0.813 HS high school, RT radiation therapy