Table 1.
Baseline Characteristics of subjects participating in the polyp prevention studies:
| Characteristic | Antioxidant Polyp Prevention Study1 (n = 864) | Calcium Polyp Prevention Study2 (n = 930) | Aspirin/Folate Polyp Prevention Study3 (n = 1121) |
|---|---|---|---|
| Age—yrs. (sd) | 61.2 ± 8.3 | 61.0 ± 9.1 | 57.5 ± 9.6 |
| Male—no. (%). | 684 (79.2) | 672 (72.3) | 409 (63.5) |
| Smoker—no. (%) | 577 (68.3) | 621 (66.8) | 638 (57.2) |
| never | 268 (31.7) | 309 (33.2) | 478 (42.8) |
| Former | 389 (46.0) | 442 (47.5) | 471 (42.2) |
| Current | 188 (22.3) | 179 (19.3) | 167 (15.0) |
| Treatment | |||
| Placebo | 214 | 466 | 169 |
| Beta-Carotene | 208 | ||
| Vitamin C/E | 217 | ||
| B, C/E | 225 | ||
| Calcium 1200 mg | 464 | ||
| Aspirin 80mg only | 169 | ||
| Aspirin 325 mg only | 167 | ||
| Aspirin 80mg/ 1 mg folate | 175 | ||
| Aspirin 325 mg/ 1 mg folate | 171 | ||
| Folate only 1 mg | 170 | ||
| Race—no. (%) | |||
| White | 733 (85.2) | 791 (85.1) | 958 (85.5) |
| African American | 58 (6.7) | 75 (8.1) | 68 (6.1) |
| Hispanic | 19 (2.2) | 27 (2.9) | 61 (5.4) |
| Other | 50 (5.8) | 37 (4.0) | 34 (3.0) |
| BMI—mean (sd) | 26.9 (4.1) | 27.4 (4.4) | 27.4 (4.5) |
| Total energy intake-calories/day (sd) | 1955.0 (757.7) | 2024 (758.6) | 1634 (667.0) |
| Carbohydrates—g/day (sd) | 201.7 (80.1) | 219.5 (82.0) | 185.9 (77.4) |
| Fat—total—g/day (sd) | 86.2 (43.0) | 87.7 (7) | 65.1 (34.3) |
| Fiber—g/day (sd) | 14.2 (7.2) | 16.4 (7.9) | 13.3 (6.0) |
| Folate—mg/day (sd) | 314.3 (165.3) | 331.3 (168.1) | 319.9 (156.6) |
| Red meat intake—servings/day (sd) | 0.54 (0.42) | 0.48 (0.38) | 0.36 (0.31) |