Table 4.
Dietary factors and the risk of serrated polyps
| Dietary variables | N Total | Serrated Polyps | P for right-left difference | Advanced Serrated Polyps | P for right-left difference | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Left | Right | Left | Right | ||||||||
|
|
|
||||||||||
| n cases | RR* (95% CI) | n cases | RR* (95% CI) | n cases | RR* (95% CI) | n cases | RR* (95% CI) | ||||
| Total Dietary Fiber | |||||||||||
| Q1 | 677 | 175 | 1.00 | 64 | 1.00 | 18 | 1.00 | 15 | 1.00 | ||
| Q2 | 676 | 185 | 1.08 (0.90 – 1.29) | 58 | 0.92 (0.65 – 1.29) | 31 | 1.47 (0.85–2.53) | 20 | 1.32 (0.69–2.50) | ||
| Q3 | 680 | 155 | 0.91 (0.75 – 1.11) | 69 | 1.06 (0.76 – 1.48) | 23 | 1.18 (0.66–2.10) | 16 | 1.09 (0.55–2.14) | ||
| Q4 | 678 | 137 | 0.88 (0.72 –1.08) | 59 | 0.95 (0.67 – 1.36) | 0.17 | 14 | 0.81 (0.42–1.57) | 16 | 1.16 (0.58–2.31) | 0.48 |
| p-trend | 0.10 | 0.99 | 0.41 | 0.83 | |||||||
| Carbohydrates | |||||||||||
| Q1 | 676 | 175 | 1.00 | 53 | 1.00 | 14 | 1.00 | 13 | 1.00 | ||
| Q2 | 679 | 175 | 1.00 (0.83 – 1.20) | 68 | 1.30 (0.92 – 1.84) | 30 | 1.95 (1.04–3.63) | 20 | 1.48 (0.76–2.87) | ||
| Q3 | 680 | 173 | 1.00 (0.83 – 1.21) | 74 | 1.38 (0.98 – 1.95) | 25 | 1.57 (0.82–3.00) | 18 | 1.28 (0.64–2.54) | ||
| Q4 | 676 | 129 | 0.82 (0.67 – 1.01) | 55 | 1.07 (0.74 – 1.56) | 17 | 0.97 (0.48–1.97) | 16 | 1.07 (0.52–2.18) | ||
| p-trend | 0.09 | 0.63 | 0.20 | 0.58 | 0.98 | 0.73 | |||||
| Fat—total | |||||||||||
| Q1 | 679 | 124 | 1.00 | 46 | 1.00 | 16 | 1.00 | 12 | 1.00 | ||
| Q2 | 679 | 165 | 1.27 (1.03 – 1.56) | 73 | 1.60 (1.12 – 2.28) | 26 | 1.53 (0.84–2.77) | 20 | 1.65 (0.85–3.21) | ||
| Q3 | 676 | 191 | 1.45 (1.19 – 1.77) | 63 | 1.36 (0.94 – 1.96) | 25 | 1.86 (1.02–3.41) | 23 | 2.38 (1.24–4.57) | ||
| Q4 | 677 | 172 | 1.27 (1.03 – 1.56) | 68 | 1.45 (1.01 – 2.10) | 19 | 1.40 (0.74–2.65) | 12 | 1.15 (0.54–2.42) | ||
| p-trend | 0.01 | 0.13 | 0.37 | 0.22 | 0.43 | 0.40 | |||||
| Red Meat | |||||||||||
| Q1 | 697 | 138 | 1.00 | 59 | 1.00 | 18 | 1.0 | 20 | 1.00 | ||
| Q2 | 681 | 164 | 1.10 (0.90 – 1.35) | 67 | 1.15 (0.82 – 1.63) | 19 | 1.00 (0.54–1.85) | 25 | 1.47 (0.82–2.63) | ||
| Q3 | 663 | 167 | 1.12 (0.91 – 1.39) | 66 | 1.15 (0.80 – 1.66) | 24 | 1.79 (0.97–3.32) | 13 | 0.95 (0.46–1.96) | ||
| Q4 | 669 | 182 | 1.17 (0.93 – 1.48) | 58 | 1.03 (0.68 – 1.57) | 0.37 | 25 | 1.93 (0.97–3.84) | 9 | 0.82 (0.34–1.96) | 0.93 |
| p-trend | 0.19 | 0.86 | 0.02 | 0.56 | |||||||
| Total energy intake | |||||||||||
| Q1 | 677 | 146 | 1.00 | 62 | 1.00 | 20 | 1.00 | 21 | 1.00 | ||
| Q2 | 678 | 153 | 1.00 (0.82 – 1.22) | 60 | 0.94 (0.67 – 1.33) | 27 | 1.77 (1.04–3.03) | 26 | 1.37 (0.79–2.37) | ||
| Q3 | 680 | 170 | 1.07 (0.88 – 1.31) | 61 | 0.93 (0.66 – 1.33) | 18 | 1.41 (0.77–2.58) | 10 | 0.59 (0.28–1.22) | ||
| Q4 | 676 | 183 | 1.16 (0.94 –1.42) | 67 | 1.01 (0.71 – 1.44) | 0.78 | 21 | 2.28 (1.23–4.24) | 10 | 0.70 (0.33–1.51) | 0.88 |
| p-trend | 0.12 | 0.96 | 0.03 | 0.14 | |||||||
*
RR adjusted for age, sex, center, treatment, time since randomization, study number, smoking status, and log calories