Table 1.
Patient Characteristics
| N=166 | |
|---|---|
| Demographics | |
| Age median, mean (SD) | 59, 59 (17) |
| Race: White n (%) | 108 (66%) |
| African-american | 53 (32%) |
| Other | 3 (2%) |
| Female gender n (%) | 61 (37%) |
| Comorbidities n (%) | |
| COPD | 20 (12%) |
| Chronic Heart Failure | 23 (14%) |
| Diabetes | 54 (31%) |
| Cancer | 17 (10%) |
| Sepsis Syndrome n (%) | |
| Sepsis | 63 (38%) |
| Severe Sepsis | 61 (37%) |
| Septic Shock | 42 (25%) |
| Severity of Disease, median, mean (SD) | |
| SOFA score | 1, 3 (3) |
| APACHE score | 14, 16 (11) |
| Lactate (mmol/L) | 2.4, 2.4 (0.8) |
| Marker levels on admission, median, mean (SD) | |
| sE-selectin (ng/mL) | 67.6, 104.2 (92.9) |
| sVCAM-1 (ng/mL) | 1,215, 1,638 (1,386) |
| ICAM-1 (ng/mL) | 202, 229 (118) |
| PAI-1 (ng/mL) | 78, 120 (167) |
| sFlt-1 (pg/mL) | 168, 333 (482) |
| IL-6 (ng/mL) | 64, 1,076 (2.684) |