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. Author manuscript; available in PMC: 2014 May 1.
Published in final edited form as: Shock. 2013 May;39(5):427–432. doi: 10.1097/SHK.0b013e3182903f0d

Table 2. Association of individual biomarkers with organ dysfunction, adjusted for age, gender and comorbid burden.

This table shows the results from each individual biomarker incorporated into a linear regression model (one marker per model) with outcome SOFA, adjusted for age (years), gender and comorbid burden. The biomarkers are standardized [biomarker – biomarker mean)/SD] so beta estimates are comparable. Each biomarker showed a statistically significant association with SOFA score.

Organ Dysfunction
Biomarker Std. beta SE P-value Model adjusted r2
sFlt 2.55 0.31 <0.001 0.36
PAI-1 1.27 0.32 <0.001 0.15
sVCAM-1 1.88 0.31 <0.001 0.24
ICAM 0.88 0.32 <0.008 0.10
sE-selectin 1.44 0.30 <0.001 0.18
IL-6 2.24 0.27 <0.001 0.34