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. Author manuscript; available in PMC: 2013 Jun 3.
Published in final edited form as: J Allergy Clin Immunol. 2010 Feb;125(2 0 2):S41–S52. doi: 10.1016/j.jaci.2009.09.046

Figure 3. Representation of the chromosomal organization of the Ig H, κ, and λ gene clusters.

Figure 3

The typical numbers of functional gene segments are shown. The κ gene cluster includes a κ deleting element that can rearrange to sequences upstream of Ck in cells that express λ chains, reducing the likelihood of dual κ and λ light chain expression.