Figure 2.

Visualization of ligand interactions with amino acid residues of H1 histamine receptor, Asp107, Lys179, Lys191, Asn198, and Trp428. Note: amino acid residues (black); native ligand of 5EH (blue); native ligand of D7V (red); (E,R)-marmin (gray); skimmianine (orange); (S)-aegeline (yellow); auraptene (green); zeorine (white); dustanine (pink); histamine (cyan); cetirizine (purple); diphenhydramine (green bright); chlorpheniramine (magenta)