Table 1. Correlations of allergic disease with SNPs in STAT genes.

Gene	Polymorphism	Disease/Phenotype	Population	References
STAT1	rs3771300	Protective for atopic sensitization	German	7
STAT2	rs2066807	Associated with asthma	Chinese and Taiwanese	8
STAT3	rs2306581, rs957971, rs1026916	Associated with decreased lung function	Caucasian	23
STAT4	T90089C	Associated with risk of mite allergen IgE production in asthmatics	Korean	37
STAT6	rs324015	Inconsistent findings with asthma correlation	Japanese, Swedish, Finnish	38, 39, 65, 67–69
STAT6	rs324015	No association with bronchial asthma, atopic dermatitis, food-related anaphylaxis, serum IgE	Japanese	65, 67
STAT6	rs324015	Associated with susceptibility to nut allergy	British Caucasian	66
STAT6	rs324011, rs4559	Associated with increased IgE levels	German and Swedish	69, 73, 74
STAT6	rs324011	Association with recurrent wheezing but not asthma susceptibility	Slovene	72
STAT6	rs1059513	Associated with increased IgE levels and bronchial responsiveness to methacholine	German and Swedish	69, 74
STAT6	rs3024974	Associated with improved lung function	Chinese	76
STAT6	rs3024975, rs841718, rs167769, rs703817	Associated with AD patients with viral skin infections (eczema herpeticum)	Caucasian	77
STAT6	GT repeat in exon 1 (A1 allele, GT13 repeat)	Increased frequency in patients with bronchial asthma, atopic dermatitis, and/or food-related anaphylaxis	Japanese	67
STAT6	GT repeat A1-A5 (GT13-GT17)	No correlation with asthma, serum IgE or bronchial responsiveness	German and Swedish	69
STAT6	GT repeat A4 (GT16)	Associated with increased numbers of peripheral eosinophils	German and Swedish	69
STAT6	GT repeat A1 allele (GT13)	Associated with atopic asthma and elevated serum IgE	American and British Caucasians	71
STAT6	GT repeat A3 allele (GT15)	Associated with asthma but not elevated serum IgE	North Indian	70