Table 2. STAT target genes in airway and skin cells.
| STAT protein | Target gene | Cell type | Stimulation | References |
|---|---|---|---|---|
| STAT3 |
Eotaxin-1/CCL11 |
HASMC |
IL-9 |
24 |
| STAT3 |
Eotaxin-1/CCL11 |
HASMC |
IL-17A |
25 |
| STAT3 |
Eotaxin-1/CCL11 |
HASMC |
Oncostatin M |
26 |
| STAT3 |
IL-6 |
HASMC |
PDGF |
29 |
| STAT3 |
IL-8/CXCL8 |
HASMC |
PDGF |
29 |
| STAT3 |
VEGF |
HASMC |
Oncostatin M |
27 |
| STAT6 |
Eotaxin-1/CCL11 |
BEAS-2B |
IL-4 and IL-13 |
113, 114 |
| STAT6 |
IL-19 |
NHBE |
IL-13 |
116 |
| STAT6 |
Eotaxin-1/CCL11 |
Human dermal fibroblasts |
IL-4 |
115 |
| STAT6 |
Eotaxin-3/CCL26 |
Human dermal fibroblasts; Esophageal epithelial cells |
IL-4 and IL-13 |
118, 119 |
| STAT6 |
P-selectin |
Human dermal microvascular endothelial cells |
IL-4 |
120 |
| STAT6 | 12/15-lipoxygenase | BEAS-2B | IL-4 | 121 |