Table 7.
Incidence of radiation-associated toxicity rates by treatment arm*
| Treatment arm | ||
|---|---|---|
| Toxicity and grade | HD-CPB (n = 322) |
ID-CPB (n = 359) |
| Skin | ||
| Grade 2 | 72 (22) | 98 (27) |
| Grade 3 | 8 (2) | 22 (6) |
| Grade 4 | 0 | 2 (<1) |
| Lung | ||
| Grade 2 | 8 (2) | 1 (<1) |
| Grade 3 | 13 (4) | 1 (<1) |
| Grade 4 | 2 (<1) | 0 |
| Leukopenia | ||
| Grade 2 | 17 (5) | 17 (5) |
| Grade 3 | 6 (2) | 6 (2) |
| Grade 4 | 0 | 0 |
| Anemia | ||
| Grade 2 | 19 (6) | 1 (<1) |
| Grade 3 | 7 (2) | 0 |
| Grade 4 | 1 (<1) | 0 |
| Thrombocytopenia | ||
| Grade 2 | 15 (5) | 1 (<1) |
| Grade 3 | 11 (3) | 0 |
| Grade 4 | 2 (<1) | 1 (<1) |
| Upper gastrointestinal | ||
| Grade 2 | 2 (1) | 0 |
| Grade 3 | 1 (<1) | 0 |
| Grade 4 | 0 | 0 |
Abbreviations as in Table 1.
Values are number (rate [%]).
*
Grade ≥2 only. Data available in 681 patients. Some patients with more than one toxicity scored. Events scored as “radiation-related,” but certainly may be related to chemotherapy. Other minor toxicities with <1% incidence are not shown (e.g., breast edema).