Table 1.
Sociodemographic and Clinical Characteristics of Patients With and Without Atypical Depression (N = 489)
| Baseline Characteristic | Atypical Depression (N = 36) | Typical Depression (N = 453) | p Value |
|---|---|---|---|
| Age, mean (SD), y | 46.1 (15.0) | 56.3 (16.7) | .0005a |
| Gender, female, N (%) | 32 (88.9) | 305 (67.3) | .0071b |
| Psychotic features, N (%) | 5 (13.9) | 139 (30.7) | .0333b |
| Race, N (%) | .5183b | ||
| White | 33 (91.7) | 414 (91.4) | |
| African American | 1 (2.8) | 26 (5.7) | |
| Other | 2 (5.5) | 13 (2.9) | |
| Treatment resistant, N (%) | 29 (80.6) | 223 (49.2) | .0014b |
| No. of MDEs, mean (SD) | 3.2 (4.2) | 2.4 (4.0) | .3544a |
| Age at onset of current MDE, mean (SD), y | 45.4 (15.5) | 55.3 (16.9) | .0008a |
| Length of current MDE, mean (SD), wk | 44.2 (74.5) | 46.2 (61.4) | .8599a |
| Age at onset of first mental illness, mean (SD), y | 25.3 (14.2) | 39.0 (19.8) | < .0001a |
| Depression severity, mean (SD) | |||
| HAM-D24 score | 32.9 (6.4) | 35.4 (7.0) | .0385a |
| IDS-SR30 score | 36.9 (20.5) | 31.7 (25.1) | .2254a |
a
p Value from independent sample t test.
b
p Value from χ2 test or Fisher exact test.
Abbreviations: HAM-D24 = 24-item Hamilton Rating Scale for Depression, IDS-SR30 = 30-item Inventory of Depressive Symptomatology–Self-report, MDE = major depressive episode.