Table 2.
Acute Phase Treatment Characteristics and Outcome for Patients With and Without Atypical Depression Receiving ECT
| Outcome | Atypical Depression (N = 36) | Typical Depression (N = 453) | p Value, Unadjusted | p Value, Adjusteda |
|---|---|---|---|---|
| Treatment Characteristic | ||||
| Seizure threshold, mean (SD) | ||||
| Total sample | 20 (10.6) | 26.3 (15.4) | .0014b | .3242 |
| Remitters only | 19.3 (10.0) | 27.2(14.7) | .0004c | .2009 |
| No. of ECT treatments, mean (SD) | ||||
| Total sample | 6.9 (3.3) | 7.2 (3.4) | .5988b | NA |
| Remitters only | 6.6 (3.1) | 7.1 (3.0) | .4230b | NA |
| Treatment Outcome | ||||
| Dropout, N (%) | 5 (13.9) | 99 (21.9) | .2610c | NA |
| Outcome, N (%)d | ||||
| Remitter | 29 (80.6) | 304 (67.1) | .0957c | .0357 |
| Nonremitter and dropout | 7 (19.4) | 149 (32.9) | NA | NA |
p Value from logistic regression; adjustment covariables: age, psychotic status, baseline HAM-D24 total score, gender, and clinical site.
p Value from independent sample t test.
p Value from χ2 test.
Adjusted odds ratio; OR interpreted as odds of remitting for atypical compared to typical groups adjusted for age, psychotic status, baseline HAM-D24 total score, gender, and clinical site; effect size (95% CI) = 2.6 (1.1 to 6.2).
Abbreviations: ECT = electroconvulsive therapy, HAM-D24 = 24-item Hamilton Rating Scale for Depression, NA = not applicable.