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Increased expression of Nrf2-dependent genes.
Primary cortical cultures were prepared and treated with 20 μM of compound 2, 10 μM of compound 7, or vehicle for 24 hours. Cells were harvested and total RNA was used for quantitative PCR. All data was standardized to GAPDH and are presented as fold change relative to the vehicle. Mean ± SEM, n = 4 (Veh), n=8 (compound 2), and n=8 (compound 7) *p < 0.05 vs. vehicle treated cells.
