Table 3. Current sequencing costs, throughput and read lengths.

Technology	Read length (bases)	Error model	Recommended sequencing depth	Cost per base (£/€/$)	Cost per 100 Mb genome (£/€/$)	Throughput (bases/ day/ instrument)	Time per 100 Mb genome per instrument (days)
Sanger dideoxy	1000–1500	Gold standard, accurate base quality, typical error probability 0.0001	10 X	10−3	106	106	103
Roche 454 FLX/FLX+	400–1000	Homopolymer errors	20–30 X	10−5	2 × 104	5 × 108	5
Illumina HiSeq2000	100–150	Typical error probability 0.01, Lower quality toward end of read	50–100 X	10−7	103	1010	1