Table 1.
Effects of T. asiatica root bark in the early phase (0-5mins) and the late phase (15-30 mins.) of the formalin test using mice
Time spent in pain behavior (secs.) | |||
---|---|---|---|
Treatment | Dose (mg / kg) | Early phase (0-5min) | Late phase (15-30min) |
Vehicle | 0 | 221.84 ± 10.56 | 190.90 ± 7.47 |
T. asiatica root bark extract | 50 | 207.54 ± 9.21 | 202.10 ± 21.29 |
100 | 212.06 ± 7.64 | 110.58 ± 8.45*** | |
200 | 181.68 ± 4.21** | 183.54 ± 11.38 | |
Indomethacin | 50 | 221.37 ± 6.71 | 25.33 ± 4.05*** |
Acetyl salicylic acid | 100 | 166.70 ±7.37*** | 153.31 ± 10.96 |
Each group represents the mean ±SEM of 8 animals.
p < 0.01
p < 0.001when compared with the control value subsequent to ANOVA