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. 2012 Jul 1;1(3):143–150. doi: 10.4161/jkst.19573

Table 1. Function of miRNAs involved in STAT3-dependent circuits in various fields of development and disease.

Field miRNA Function References
Embryonic
development
miR-93, miR-17-5p
Germ layer differentiation
18
miR-17, miR-20a, miR-106b
Lung branching morphogenesis
21
miR-124a, miR-9
Neural lineage differentiation
19, 20
Immunity and infection disease
miR-125b
Myeloid cell proliferation
22, 23
miR-17-5p, miR-20a
Proliferation of myeloid derived suppressor cells
24
miR-155
Innate antiviral immunity in HBV-infection
27
let-7a
Progression of hepatitis B to hepatocellular carcinoma
23
Cancer disease
miR-21, miR-19a/b
Involvement in multiple myeloma
34, 15, 36, 37
miR-21, miR-181b
Involvement in colon adenocarcinoma
38
miR-155, miR-20b
Involvement in breast cancer
35
miR-9, miR-17, miR-20a
Involvement in glioma
32
Cardiovascular system
miR-199a
Sarcomere protein ubiquitination and turnover sarcomere integration
16
Myocardial vascular function
16
miR-21
Regeneration through MSCs
48
Pulmonary hypertension miR-17-5p, miR-20a
Fibrous matrix production
50
miR-204 Vascular remodeling 52