Table 1.
Action potential properties of HD and WT fibers
| Parameter | Resting membrane potential (mV) | Max rate-of-rise (mV/ms) | Max Δvoltage (mV) | Decay τ1 (ms) | Decay τ2 (ms) |
| WT (n = 17) | −87 ± 1 | 420 ± 33 | 127 ± 3 | 0.62 ± 0.04 | 7.7 ± 0.4 |
| HD (n = 12) | −86 ± 1 | 465 ± 47 | 125 ± 2 | 0.82 ± 0.06* | 15.0 ± 2.1* |
Average values (±SEM) of the resting or baseline membrane potential, the maximum rate-of-rise of the depolarization, the peak change in membrane potential, the initial repolarization time constant (τ1), and the slower repolarization time constant (τ2). * indicates a significant difference compared to WT fibers (P < 0.05).