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Conservation of eight ancestral bilaterian peptide precursor families. Conserved features of these eight peptide precursor families include key residues shown in the peptide logo. For example, the N-terminal glutamine in GnRH/AKH sequences, pairs of cysteines in AVP and Calc/DH31 sequences, the position of peptide(s) and other domains inside the precursor sequence, and constrained length distribution of spacer sequences in the precursor (shown by histograms).
