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. 2013 May 3;135(21):8001–8015. doi: 10.1021/ja402016p

Figure 3.

Figure 3

Chemical structures of the metabolites formed during oxidation of diclofenac. 4′-Hydroxydiclofenac (7) is the major metabolite formed during oxidation by CYP2C9. 5-Hydroxydiclofenac (8) is the major metabolite formed during oxidation by CYP3A4.