Table 5. CRP level according to serum levels of IL-6 and IL-1β in patients with gemcitabine monotherapy for advanced pancreatic cancer.
| IL-6/IL-1β classification | N | Median (95% CI) (mg dl−1) | P-value |
|---|---|---|---|
| IL-6Low/IL-1βLow |
25 |
0.13 (0.06–0.25) |
Ref. |
| IL-6Low/IL-1βHigh |
5 |
0.08 (NA) |
0.140 |
| IL-6High/IL-1βLow |
15 |
1.19 (0.17–2.79) |
0.001 |
| IL-6High/IL-1βHigh | 15 | 5.61 (2.83–10.09) | <0.001 |
Abbreviations: CI=confidence interval; CRP=C-reactive protein; HR=hazard ratio; IL=interleukin; NA=not applicable; OS=overall survival; PFS=progression-free survival.