Table 4. Overall detection rates of rare BRAF mutations with different methods.
| Reference | Pyrosequencing | Pyrosequencing/Sanger sequencing | COBAS | Immunohistochemistry BRAF V600E |
|---|---|---|---|---|
| Patients |
92.9% (13/14a) |
100% (14/14) |
50.0% (7/14) |
21.4% (3/14) |
| Samples | 95.5% (42/44b) | 100% (44/44) | 44% (8/18) | 27.8% (5/18) |
Including two patients where mutations could not be fully classified.
Including six samples where mutations could not be fully classified.