Table 3b. Cox regression of colorectal cancer cases in the CRUMS cohort.

N	UnivariateHR (CI 95%)	MultivariateHR (CI 95%)
Quadruple Index
372	1.220 (0.881–1.689)	1.157 (0.827–1.619)
KRAS
378	1.761 (1.220–2.542)	1.485 (1.023–2.155)
BRAF
377	0.843 (0.508–1.397)	0.914 (0.529–1.576)
PIK3CA Exon20
372	0.000 (0.000–1.408 E+122)	0.000 (0.000–1.088E169)
PTEN
377	0.870 (0.531–1.426)	0.862 (0.519-1.431)

Abbreviations: Cl=confidence interval; CRUMS=Colorectal Cancer in Umeå Study; HR=hazard ratio

HR determined by Cox proportional hazard models, adjusted for sex, age, tumour site and tumour stage.