Table 4. Multivariate analysis of disease-free survival.
| Adjusted HR (95% CI) | P-value | |
|---|---|---|
|
Histology | ||
| MAC | 7.96 (3.76–16.8) | <0.001 |
| Non-MACa |
1 |
|
|
T stage | ||
| T4 | 1.94 (1.13–3.34) | 0.017 |
| T1–3 |
1 |
|
|
N stage | ||
| N2 | 2.39 (1.48–3.85) | <0.001 |
| N0–1 |
1 |
|
|
Angiolymphatic invasion | ||
| Present | 2.83 (1.64–4.87) | <0.001 |
| Absent |
1 |
|
|
Perineural invasion | ||
| Present | 2.27 (1.36–3.79) | 0.002 |
| Absent | 1 | |
Abbreviations: CI=confidence interval; HR=hazard ratio; MAC=mucinous adenocarcinoma.
a
Non-MAC includes non-mucinous adenocarcinoma and adenocarcinoma with intermediate mucinous component.