Table 5. Cox's proportional hazards model including all molecules under study in the entire cohort (n=72 patients, model A), as well as in glioblastomas (n=51, model B).
| HR | P-value | 95% CI of HR | ||
|---|---|---|---|---|
|
A | ||||
| SOX11 expression | 0.975 | 0.009 | 0.957 | 0.994 |
| Histological grade (II vs III vs IV) | 1.952 | 0.016 | 1.135 | 3.358 |
| Patients' age | 1.037 | 0.002 | 1.013 | 1.062 |
| Expression subgroup (Subgroups 1/2 vs 3/4) | 1.032 | 0.922 | 0.552 | 1.927 |
| Administration of radiotherapy (Yes vs no) | 0.369 | 0.013 | 0.169 | 0.809 |
|
Surgery
(Partial vs complete) |
0.870 |
0.689 |
0.441 |
1.717 |
|
B | ||||
| SOX11 expression | 0.339 | 0.010 | 0.149 | 0.771 |
| Patients' age | 1.043 | 0.018 | 1.007 | 1.080 |
| Expression subgroup (Subgroups 1/2 vs 3/4) | 1.002 | 0.836 | 0.987 | 1.017 |
| Administration of radiotherapy (Yes vs no) | 0.373 | 0.043 | 0.144 | 0.967 |
| Surgery (Partial vs complete) | 1.042 | 0.917 | 0.481 | 2.258 |
Abbreviations: CI=confidence interval; HR=hazard ratio.
Bold entries indicate statistical significance.